Available Reagents

Available Nonhuman Primate Reagents.

Available Reagents - NIH Nonhuman Primate Reagent Resource

Available Nonhuman Primate Reagents
Select a Reagent Category:
 
  Antibodies for In
Vitro Diagnostics
Reagents for In Vivo
Administration
NHP Cell Lines
and Viruses
Immunoglobulin
Reference Reagents
NHP Recombinant
Proteins
Antibodies for In Vivo Administration
Product (Details/Order)
Description
[Collapse]Group: Cell-depleting antibodies
 [Collapse]Sub-Group:
  [Collapse]Target: CD16
   Depleting anti-CD163G8: Mouse anti-human CD16, NK cell-depleting antibody. (Available only in 200mg units at 10mg/ml.)
  [Collapse]Target: CD20
   Depleting anti-CD20 (rhesus recombinant)CD20-2B8R1: mouse/rhesus CDR-grafted form of the depleting anit-CD20 antibody, rituximab.
  [Collapse]Target: CD3
   CD3-immunotoxinRecombinant CD3 (FN18) diphtheria toxin. Fusion protein composed of an affinity-matured form of FN18 expressed as a single chain diabody DT fusion protein (Prot Eng Design Select 2007; 20: 425)
  [Collapse]Target: CD4
   Depleting anti-CD4 (human recombinant)huOKT4A: Humanized, depleting anti-CD4 antibody. REAGENT WILL BE DISCONTINUED AFTER JANUARY 2011.
   Depleting anti-CD4 (rhesus recombinant)CD4R1: Rhesus recombinant CDR-grafted anti-CD4 antibody. Rhesus IgG1 heavy chain. (Replaces humanized OKT4A.)
  [Collapse]Target: CD8
   Depleting anti-CD8alpha (rhesus recombinant)M-T807R1: mouse/rhesus CDR-grafted form of the depleting anti-CD8a antibody, M-T807. (Available only in 200mg units at 10mg/ml.)
   Depleting anti-CD8beta (rhesus recombinant)CD8b255R1: Rhesus recombinant CDR-grafted anti-CD8b antibody [New Reagent]
  [Collapse]Target: Rhesus anti-Thymocyte Globulin
   Anti-rhesus Thymocyte GlobulinPurified rabbit IgG from serum of rabbits immunized with rhesus thymocytes. Available to NIH Investigators only.
[Collapse]Group: Control antibodies
 [Collapse]Sub-Group:
  [Collapse]Target:
   Control antibody: Human/mouse chimericRecombinant control antibody, 1129. V-regions from a mouse anti-RSV antibody; C-regions from human IgG1K.
   Control antibody: Mouse IgG2aControl mouse IgG2a secreted by hybridoma 20-8-4S (anti-mouse MHC class-I)
   Control antibody: Rhesus recombinant IgG1Rhesus IgG1 with CDRs grafted from an irrelevant (anti-desmipramine) monoclonal antibody. Serves as an irrelevant control antibody for other rhesus recombinant antibodies such as anti-CD8
   Control antibody: Human IgG1Control Human IgG1: Fully human antibody directed against an irrelevant antigen (a bacterial toxin).
   Control antibody: Mouse IgG1Control mouse IgG1. Antibody is directed against an irrelevant antigen (a bacterial toxin). (Available only in 200mg units at 10mg/ml.)
   IgIVControl human Ig - 50 mg/ml
[Collapse]Group: Other antibodies
 [Collapse]Sub-Group:
  [Collapse]Target:
   Anti-alpha-4/beta-7 integrinRecombinant anti-alpha4/beta7 integrin engineered as a rhesus IgG1
   Human IFN-gamma R/Ig fusion proteinHuman IFN-gamma receptor fused to human IgG2 Fc
  [Collapse]Target: CD154
   Human/mouse chimeric anti-CD154Recombinant anti-CD154 antibody. V-regions from mouse 5C8 clone; C-regions human IgG1k.
   Mouse anti-CD154 (NC8A4)Mouse monoclonal antibody, NC8A4, against CD154. In vivo activity undetermined.
  [Collapse]Target: CD2
   Anti-CD2, LoCD2bR1Rhesus recombinant antibody based on the CDRs of the rat anti-primate anti-CD2 antibody, LoCD2b.
  [Collapse]Target: CD40
   Anti-CD40 (2C10R1, recombinant)Rhesus recombinant (chimeric) form of 2C10. Constant regions are rhesus IgG1k.
   Anti-CD40 (2C10R4, recombinant)Rhesus recombinant (chimeric) form of 2C10. Constant regions are rhesus IgG4k.
   Anti-CD40 (3A8R1, recombinant)Rhesus recombinant (chimeric) form of 3A8. Constant regions are rhesus IgG1k.
   Anti-CD40 (3A8R4, recombinant)Rhesus recombinant (chimeric) form of 3A8. Constant regions are rhesus IgG4k.
   Anti-CD40 (mouse 3A8)3A8: Mouse antibody against macaque CD40.
  [Collapse]Target: IL-10
   Anti-IL-10 (rhesus recombinant)Rhesus recombinant (CDR-grafted) antibody that neutralizes rhesus IL-10 in vivo and in vitro
  [Collapse]Target: IL-15
   Anti-IL-15 (rhesus recombinant)Rhesus recombinant (CDR-grafted) antibody that neutralizes rhesus IL-15 in vitro and in vivo
  [Collapse]Target: PD-1
   Anti-PD-1 (rhesus recombinant)Rhesus recombinant antibody (rhesus/human chimeric) comprising silenced rhesus IgG4k constant regions and variable regions from anti-human PD-1, nivolumab.
   Anti-PD-1 (rhesus recombinant)

Recombinant antibody comprising rhesus IgG4*k  constant regions and variable regions from the anti-PD-1 antibody pembrolizumab.