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The Resource for your Nonhuman Primate Research

We support innovation, reproducibility, and translation of preclinical research with high-quality biological development. We offer primate antibodies and recombinant proteins for pre-clinical NHP studies, NHP-specific reagents for in vitro assays, and have an industry wide antibody reactivity database for NHP species.

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News and Announcements

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Link to News Archives

https://www.nhpreagents.org/NewsUpdates

2024 December 04

SHIV remission in macaques with early treatment initiation and ultra long-lasting antiviral activity.

Daly, Michele B Dinh, Chuong Holder, Angela Rudolph, Donna Ruone, Susan Swaims-Kohlmeier, Alison Khalil, George Sharma, Sunita Mitchell, James Condrey, Jillian Kim, Daniel Pan, Yi Curtis, Kelly Williams, Peter Spreen, William Heneine, Walid García-Lerma, J Gerardo

Nat Commun

Anti-CD8 alpha [MT807R1]

2024 November 01

A model of lymphocryptovirus-associated post-transplant lymphoproliferative disorder in immunosuppressed Mauritian cynomolgus macaques.

Wu, Helen L Weber, Whitney C Waytashek, Courtney M Boyle, Carla D Reed, Jason S Bateman, Katherine B Fisher, Hannah K Chen, Yan Armantrout, Kimberly Swanson, Tonya Shriver-Munsch, Christine Northrup, Mina Fischer, Miranda Biswas, Sreya Templon, John Panoskaltsis-Mortari, Angela Burwitz, Benjamin J Johnson, Amanda L Colgin, Lois Lewis, Anne D Smedley, Jeremy V Axthelm, Michael K Skalsky, Rebecca Meyers, Gabrielle Maziarz, Richard T Mittra, Erik Berg, Melissa Stanton, Jeffrey J Sacha, Jonah B

PLoS Pathog

Anti-CD8 beta [CD8b255R1] Anti-CD8 alpha [MT807R1] Anti-CD20 [2B8R1F8]-Afucosylated

2024 July 23

Knockdowns of CD3zeta chain in Primary NK Cells Illustrate Modulation of Antibody-Dependent Cellular Cytotoxicity against Human Immunodeficiency Virus-1.

Sugawara, Sho Lee, Esther Craemer, Melissa Pruitt, Alayna Balachandran, Harikrishnan Gressens, Simon Kroll, Kyle Manickam, Cordelia Li, Yuxing Jost, Stephanie Woolley, Griffin Reeves, R Keith

AIDS Res Hum Retroviruses

Anti-CD4 [CD4R1]

2024 July 18

Suppression of viral rebound by a Rev-dependent lentiviral particle in SIV-infected rhesus macaques.

Hetrick, Brian Siddiqui, Summer Spear, Mark Guo, Jia Liang, Huizhi Fu, Yajing Yang, Zhijun Doyle-Meyers, Lara Pahar, Bapi Veazey, Ronald S Dufour, Jason Andalibi, Ali Ling, Binhua Wu, Yuntao

Gene Ther

Anti-CD8 alpha [MT807R1]

News & Updates:

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2024 Aug 23

mAbsolve Parnership for Fc-silenced STR Antibodies

Today, we celebrate a milestone—partnering with mAbsolve to incorporate ‘STR’ mutations into our antibodies. This ensures targeted action without unintended immune responses, boosting rigor, effectiveness, and safety. By decreasing Fc-mediated interference (hello Fc-block!) and enhancing the signal-to-noise ratio, STR-enhanced antibodies will produce more robust and reproducible scientific findings. Expect many STR-enhanced antibodies soon!

For your Acknowledgements section

Reagents used in these studies were provided by the NIH Nonhuman Primate Reagent Resource (P40 OD028116, U24 AI126683).

2024 Apr 11

NHPRR Linkedin

Follow our newest publications, products, and messages on LinkedIn!

RRID Citation on Materials and Methods

For your Materials & Methods section: The rhesus recombinant Anti-CD8 beta [CD8b255R1] monoclonal antibody was engineered and produced by the Nonhuman Primate Reagent Resource (NIH Nonhuman Primate Reagent Resource Cat# PR-2557, RRID:AB_2716321)

Anti-CD8 beta [CD8b255R1]

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Sharing Your Data: Our community-based reactivity database is built by users like you. Share your results!

Requesting a Reagent: We develop NHP-specific antibodies based on investigator-initiated requests, including: recombinant proteins for cell depletion, receptor activation, cytokine neutralization, co-stimulatory blockade, immunosuppression.

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Sharing Your Publication: If you’ve recently published a study using an NHPRR reagent, add it to the publication database.

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The Nonhuman Primate Reagent Resource (NHPRR) is a nonprofit laboratory established in 1999, and supported by the National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), and Office of Research Infrastructure Programs (ORIP).