The Resource for your Nonhuman Primate Research

We support innovation, reproducibility, and translation of preclinical research with high-quality biological development. We offer primate antibodies and recombinant proteins for pre-clinical NHP studies, NHP-specific reagents for in vitro assays, and have an industry wide antibody reactivity database for NHP species.

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NHP Reactivity

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2025 May 20

B cell lines fail to support efficient rhesus enteric calicivirus and human norovirus replication.

Farkas, Tibor

J Virol

Reactivity Database or Legacy Product

2025 May 20

Development and optimization of human T-cell leukemia virus-specific antibody-dependent cell-mediated cytotoxicity (ADCC) assay directed to the envelope protein.

Pise-Masison, Cynthia A Rahman, Mohammad Arif Masison, Daniel C Gutowska, Anna Moles, Ramona Bissa, Massimiliano Sarkis, Sarkis Schifanella, Luca Zhou, Tongqing Jones, Jennifer Jacobson, Steve Franchini, Genoveffa

J Virol

Control antibody rhesus IgG1 (anti-DSP) [DSPR1] Anti-CD8 alpha [MT807R1]

2025 May 19

SIV/SARS-CoV-2 coinfection in rhesus macaques impacts viral shedding, host immunity, the microbiome, and viral evolution

Fredericks, Megan N.; Kolodner, Zohar; Waalkes, Adam; Sawatzki, Kaitlin; Hao, Linhui; Long, Dustin R.; Penewit, Kelsi; Midkiff, Cecily C.; McCormick, Carter J.; Beraki, Semira; Edlefsen, Paul T.; Barrow, Jeana; Greninger, Alexander L.; Gale, Michael; Blair, Robert V.; Salipante, Stephen J.; Fuller, Deborah H.; O’Connor, Megan A.

Frontiers in immunology

Reactivity Database or Legacy Product

2025 May 15

Convergence and divergence of B cell responses in two HIV-1 Env immunizations in Rhesus macaques.

DeLuca, Jenna M Blasi, Maria McGee, Taylor J Jha, Shalini Shen, Xiaoying Gu, Shuqin Pollara, Justin Kerkau, Melissa Purwar, Mansi Carnathan, Diane G Negri, Donatella Cara, Andrea Wollenberg, Kurt Wiehe, Kevin Saunders, Kevin O Lu, Shan Silvestri, Guido Weiner, David B Klotman, Mary E Ferrari, Guido Anthony Moody, M Bonsignori, Mattia

Commun Med (Lond)

Cell line secreting Herpesvirus Papio [S594]

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2024 Aug 23

mAbsolve Parnership for Fc-silenced STR Antibodies

Today, we celebrate a milestone—partnering with mAbsolve to incorporate ‘STR’ mutations into our antibodies. This ensures targeted action without unintended immune responses, boosting rigor, effectiveness, and safety. By decreasing Fc-mediated interference (hello Fc-block!) and enhancing the signal-to-noise ratio, STR-enhanced antibodies will produce more robust and reproducible scientific findings. Expect many STR-enhanced antibodies soon!

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2024 Apr 09

For your Acknowledgements section

Reagents used in these studies were provided by the NIH Nonhuman Primate Reagent Resource (P40 OD028116, U24 AI126683).

2024 Apr 11

NHPRR Linkedin

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2024 Apr 09

RRID Citation on Materials and Methods

For your Materials & Methods section: The rhesus recombinant Anti-CD8 beta [CD8b255R1] monoclonal antibody was engineered and produced by the Nonhuman Primate Reagent Resource (NIH Nonhuman Primate Reagent Resource Cat# PR-2557, RRID:AB_2716321)

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The Nonhuman Primate Reagent Resource (NHPRR) is a nonprofit laboratory established in 1999, and supported by the National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), and Office of Research Infrastructure Programs (ORIP).

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