The Resource for your Nonhuman Primate Research

We support innovation, reproducibility, and translation of preclinical research with high-quality biological development. We offer primate antibodies and recombinant proteins for pre-clinical NHP studies, NHP-specific reagents for in vitro assays, and have an industry wide antibody reactivity database for NHP species.

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NHP Reactivity

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2025 July 01

Allogeneic Liver Transplantation in Nonhuman Primates: Surgical Technique With Stable Postoperative Outcomes.

Tomofuji, Katsuhiro Cloonan, Daniel J Coe, Taylor M Bourgeois, Olivia Matheson, Rudy Karadagi, Ahmad Kharga, Anil Tomosugi, Toshihide Markmann, James F Kimura, Shoko

Transplant Direct

Anti-CD154 [5C8H1]

2025 June 24

Transient glycan shield reduction induces CD4-binding site broadly neutralizing antibodies in SHIV-infected macaques.

Morris, Daniel J Gorman, Jason Zhou, Tongqing Lora, Jinery Connell, Andrew J Li, Hui Liu, Weimin Roark, Ryan S Campion, Mary S Carey, John W Habib, Rumi Li, Yingying Martella, Christian L Park, Younghoon Singh, Ajay Sowers, Kirsten J Teng, I-Ting Wang, Shuyi Chohan, Neha Ding, Wenge Lauer, Craig Lewis, Emily Mason, Rosemarie D Rando, Juliette M Peyton, Lowrey Schramm, Chaim A Wagh, Kshitij Korber, Bette Seaman, Michael S Douek, Daniel C Haynes, Barton F Kulp, Daniel W Roederer, Mario Hahn, Beatrice H Kwong, Peter D Shaw, George M

Cell Rep

Anti-CD8 beta [CD8b255R1] Anti-CD8 alpha [MT807R1]

2025 June 20

Distinct transcriptomic signatures in pulmonary tissue resident and vascular resident-like T cells in nonhuman primates.

Melton, Alexandra Potter, E Lake Penney, Toni Krzykwa, Clara Rowe, Lori A Goff, Kelly Scheuermann, Sarah E Russell-Lodrigue, Kasi Melton, Hunter J Magnani, Diogo M Kolls, Jay K Blair, Robert V Maness, Nicholas J

iScience

Anti-CD45 [ITS_rhCD45]-AF647

2025 June 17

SARS-CoV-2 Receptor Binding Domain (RBD) Protein-Protein Conjugate Induces Similar or Better Antibody Responses as Spike mRNA in Rhesus Macaques.

Scaria, Puthupparampil V Rowe, Christopher G Kosik, Ivan Hu, Zhe Renn, Jonathan P Alani, Nada Kemanli, Pinar Orr-Gonzalez, Sachy Lambert, Lynn E Adeyemi, Kayode Doritchamou, Justin Y A Barnafo, Emma K Rausch, Kelly M Muslinkina, Liya Morrison, Robert D Todd, John-Paul Esposito, Dominic Lees, Andrew Yewdell, Jonathan Duffy, Patrick E

Vaccines (Basel)

Anti-rhesus IgG1/3 [1B3]-HRP Anti-rhesus IgG4 [tessera]-biotin Anti-rhesus IgG2 [dio] Anti-rhesus IgG1 [ena]

News & Updates:

2024 Aug 23

mAbsolve Parnership for Fc-silenced STR Antibodies

Today, we celebrate a milestone—partnering with mAbsolve to incorporate ‘STR’ mutations into our antibodies. This ensures targeted action without unintended immune responses, boosting rigor, effectiveness, and safety. By decreasing Fc-mediated interference (hello Fc-block!) and enhancing the signal-to-noise ratio, STR-enhanced antibodies will produce more robust and reproducible scientific findings. Expect many STR-enhanced antibodies soon!

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2024 Apr 09

For your Acknowledgements section

Reagents used in these studies were provided by the NIH Nonhuman Primate Reagent Resource (P40 OD028116, U24 AI126683).

2024 Apr 11

NHPRR Linkedin

Follow our newest publications, products, and messages on LinkedIn!

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2024 Apr 09

RRID Citation on Materials and Methods

For your Materials & Methods section: The rhesus recombinant Anti-CD8 beta [CD8b255R1] monoclonal antibody was engineered and produced by the Nonhuman Primate Reagent Resource (NIH Nonhuman Primate Reagent Resource Cat# PR-2557, RRID:AB_2716321)

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Sharing Your Data: Our community-based reactivity database is built by users like you. Share your results!

Requesting a Reagent: We develop NHP-specific antibodies based on investigator-initiated requests, including: recombinant proteins for cell depletion, receptor activation, cytokine neutralization, co-stimulatory blockade, immunosuppression.

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Sharing Your Publication: If you’ve recently published a study using an NHPRR reagent, add it to the publication database.