The Resource for your Nonhuman Primate Research

We support innovation, reproducibility, and translation of preclinical research with high-quality biological development. We offer primate antibodies and recombinant proteins for pre-clinical NHP studies, NHP-specific reagents for in vitro assays, and have an industry wide antibody reactivity database for NHP species.

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NHP Reactivity

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2025 August 20

The Immunogenicity of AAV-Encoded HIV-1 bNAbs in Rhesus Macaques Is Unaffected by a Short Course of the Immunomodulator CTLA4Ig.

Hahn, Patricia A Shandilya, Siddhartha da Costa, Lucas A B da Silva, Laura C F O'Hagan, Daniel Liang, Brian Engelman, Kathleen Gardner, Matthew R Gao, Guangping Fuchs, Sebastian P Martinez-Navio, Jose M Desrosiers, Ronald C Ardeshir, Amir Magnani, Diogo M Martins, Mauricio A

AIDS Res Hum Retroviruses

Rhesus CTLA-4-Ig Fusion Protein [XPROR1LALALS]

2025 July 30

Determinants of successful AAV-vectored delivery of HIV-1 bNAbs in early life.

Ardeshir, Amir O'Hagan, Daniel Mehta, Isha Shandilya, Siddhartha Hopkins, Lincoln L J Adamson, Lourdes Kuroda, Marcelo J Hahn, Patricia A da Costa, Lucas A B Fuchs, Sebastian P Martinez-Navio, Jose M Gardner, Matthew R Van Rompay, Koen K A Magnani, Diogo M Lifson, Jeffrey D Gao, Guangping Farzan, Michael Desrosiers, Ronald C Das, Jishnu Martins, Mauricio A

Nature

Anti-HIV [rh3BNC117] Anti-HIV [rh3BNC117LS]

2025 July 01

Allogeneic Liver Transplantation in Nonhuman Primates: Surgical Technique With Stable Postoperative Outcomes.

Tomofuji, Katsuhiro Cloonan, Daniel J Coe, Taylor M Bourgeois, Olivia Matheson, Rudy Karadagi, Ahmad Kharga, Anil Tomosugi, Toshihide Markmann, James F Kimura, Shoko

Transplant Direct

Anti-CD154 [5C8H1]

2025 June 24

Transient glycan shield reduction induces CD4-binding site broadly neutralizing antibodies in SHIV-infected macaques.

Morris, Daniel J Gorman, Jason Zhou, Tongqing Lora, Jinery Connell, Andrew J Li, Hui Liu, Weimin Roark, Ryan S Campion, Mary S Carey, John W Habib, Rumi Li, Yingying Martella, Christian L Park, Younghoon Singh, Ajay Sowers, Kirsten J Teng, I-Ting Wang, Shuyi Chohan, Neha Ding, Wenge Lauer, Craig Lewis, Emily Mason, Rosemarie D Rando, Juliette M Peyton, Lowrey Schramm, Chaim A Wagh, Kshitij Korber, Bette Seaman, Michael S Douek, Daniel C Haynes, Barton F Kulp, Daniel W Roederer, Mario Hahn, Beatrice H Kwong, Peter D Shaw, George M

Cell Rep

Anti-CD8 beta [CD8b255R1] Anti-CD8 alpha [MT807R1]

News & Updates:

2024 Aug 23

mAbsolve Parnership for Fc-silenced STR Antibodies

Today, we celebrate a milestone—partnering with mAbsolve to incorporate ‘STR’ mutations into our antibodies. This ensures targeted action without unintended immune responses, boosting rigor, effectiveness, and safety. By decreasing Fc-mediated interference (hello Fc-block!) and enhancing the signal-to-noise ratio, STR-enhanced antibodies will produce more robust and reproducible scientific findings. Expect many STR-enhanced antibodies soon!

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2024 Apr 09

For your Acknowledgements section

Reagents used in these studies were provided by the NIH Nonhuman Primate Reagent Resource (P40 OD028116, U24 AI126683).

2024 Apr 11

NHPRR Linkedin

Follow our newest publications, products, and messages on LinkedIn!

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2024 Apr 09

RRID Citation on Materials and Methods

For your Materials & Methods section: The rhesus recombinant Anti-CD8 beta [CD8b255R1] monoclonal antibody was engineered and produced by the Nonhuman Primate Reagent Resource (NIH Nonhuman Primate Reagent Resource Cat# PR-2557, RRID:AB_2716321)

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